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Protein/Antibody Analytical Tool Enzymes

Analysis Enzymes
IdeZ Protease
IdeZ Protease

IdeZ protease from Yinjia Bio is recombinantly expressed in Escherichia coli. This enzyme recognizes IgG antibodies from human, mouse, sheep, monkey, and rabbit, and specifically cleaves below the hinge region, digesting IgG into F(ab’)₂ and Fc fragments. Compared with IdeS protease, IdeZ protease is more efficient in cleaving IgG2a.

 

Product images are for reference only.


Details

     

    Applications

    Structural characterization of therapeutic antibodies, Fc-fusion proteins and antibody-drug conjugates.

     

    Advantages

    (1)Strict substrate specificity, recognizing only IgG.

    (2)High cleavage activity against mouse IgG2a.

     

    Information

    (1)Product Name: IdeZ Protease

    (2)Catalog No. : YJ-O-177

    (3)Size: 1 KU / 2 KU

    (4)Storage temperature: -20 °C


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